Document Details

Document Type : Project 
Document Title :
Identify genetic mutations in the FLT3 gene in patients with cancer of the blood in the Kingdom of Saudi Arabia
التعرف على الطفرات الجينية في FLT3 جين في مرضى سرطان الدم في المملكة العربية السعودية
 
Document Language : Arabic 
Abstract : Leukemia (leukemia) can be defined as non-cancerous Khalaiaaldm Alda mature in the bone marrow. This disease of acute leukemia can be divided into two main types of acute leukemia in granulosa cells (Meuload leukemia) and acute leukemia cells in non-trotted (Amphouid to leukemia). Almioleod to acute leukemia is divided into eight groups of M0-M7. This type of cancers that can be easily diagnosed by the presence of immature cells by more than 30% in the bone marrow and then in the blood. There is some research confirms that genetic mutations that occur in some cellular receptors in the stem cells in bone marrow of patients with cancer of the blood to have an important role in the evolution of the disease. Among these cellular receptors FLT3 future, a future Altairosen Kanez (Receptor Tyrosine kinases), a category No. 3 of those receptors. This group of receptors have an important role to the growth and proliferation of stem cells in bone marrow and on this basis of any genetic mutations in the gene may account for the future FLT3 might lead to an imbalance in the growth of these stem cells, leading to developments in the disease. There are no studies in this country so far to study that subject. In this sense, the main objective of this research is to identify all the genetic mutations in the gene for Msqubl FLT3 in patients with cancer of the blood in the Kingdom of Saudi Arabia and compared these mutations with the development of the disease and therefore accurate diagnosis of the disease so that doctors diagnose and treat the disease in high precision. Finally, calculate the proportion of the presence of this genetic mutation in all patients in our Kingdom. 
Publishing Year : 1425 AH
2005 AD 
Sponsor Name : kau 
Sponsorship Year : 1425 AH
2005 AD 
Added Date : Wednesday, April 30, 2008 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
ممدوح عبدالله قاريqari, mamdouh abdullahInvestigatorDoctorate 

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