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Document Type |
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Project |
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Document Title |
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A Prospective Study of Congenital Anomalies (Malformations) Among Live Born Neonates at King Abdulaziz University Hospital دراسة استطلاعية من تشوهات خلقية (تشوهات) ومن مباشرة حديثي الولادة الذين ولدوا في مستشفى جامعة الملك عبدالعزيز |
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Subject |
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Department of Pediatrics |
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Document Language |
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Arabic |
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Abstract |
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Major congenital anomalies are the leading cause of early neonatal death and childhood handicap with significant social and economic burden on the family and community. The aim of this project is to estimate incidence and pattern of major and minor congenital malformations among live born neonates in Jeddah, Saudi Arabia and to establish guidelines for accurate diagnosis. Estimation of importance of risk factors such as maternal age and disease as well as consanguinity for occurrence of malformation.
Between March 2004 and May 2005 a total of 5356 babies born of them 5356 were live birth consecutively in King Abdulaziz University Hospital, Jeddah, Saudi Arabia, were surveyed for the presence of major and minor congenital anomalies. A total of 147 (27.07/1000 total birth) live birth and 13 (2.39/1000 total birth) Still birth had congenital anomalies. In the live birth the incidence of major and minor congenital anomalies were 93.9% and 6.1% respectively. The incidence of congenital anomalies were insignificantly differ between Saudi and non- Saudi (55.8% versus 44.2%, p>0.05) and between male and female (53.7% versus 46.3%, p>0.05). The incidence of congenital anomalies for infant of diabetic mother was 3.4% and for cardiac mother 0.7% and for healthy mother 95.9%. The high incidence of congenital anomalies were for CVS (25.2%), followed by musculoskeletal/limb (13.6%), then external genitalia (10.2%), then urinary system (9.5%), then multiple chromosomal (8.8%), then orofacial (7.5%), then CNS (6.8%), then skin (6.1%), then multiple single gene (4.8%), then eyes (2.7%), then multiple sequence (2.0%), followed by unclassified (2%), musculoskeletal/abdominal (0.7%) and endocrine (0.7%). High incidence of major malformation in Jeddah. The importance of Genetic Counseling is revealed in our study since more than three quarters of mothers were under 36 years old, and may well plan future pregnancies |
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Publishing Year |
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1424 AH
2004 AD |
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Added Date |
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Monday, November 9, 2009 |
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Researchers
| نادية محمد فدا | fida, Nadia mohammed | Investigator | Doctorate | |
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